5-Choice Serial Reaction Time Task

From Wikipedia, the free encyclopedia
Jump to: navigation, search

The Five-Choice Serial Reaction-Time Task (5CSRTT) is a laboratory model of visuospatial attention and motor impulsivity used in psychological research.[1][2] The task takes place within an operant chamber with at least five holes (apertures) that can illuminate, and a food tray to deliver reward. The 5CSRTT requires the animal (typically a rat, although mice can also be used[3]) to correctly identify which of the five apertures is illuminated, via a nose poke, in order to receive a sugar reward. The difficulty of the task is controlled by the length of time the aperture is illuminated: a shorter illumination time requires the animal to pay greater attention, and thus is more difficult (as shown by decreased accuracy).[4] Between every trial, there is also a short interval wherein the animal must withhold all responses, and any responding during this interval is met with a brief time-out and recorded as a failure of inhibitory control.

Because the 5CSRTT has separate measures of attention, impulsivity, and reaction times, it has proven useful in the pre-clinical study of the treatment of diagnoses such as attention-deficit/hyperactivity disorder,[5] and is also a pre-cursor to modern rodent models of gambling[6] and decision making.[7]

See also[edit]

References[edit]

  1. ^ "The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry". Psychopharmacology (Berl.) 163 (3-4): 362–80. October 2002. doi:10.1007/s00213-002-1154-7. PMID 12373437. 
  2. ^ "The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats". Retrieved 8 March 2010. 
  3. ^ Lustig, C. "CNTRICS final animal model task selection: control of attention". Neuroscience & Behavioral Reviews 37 (9B): 2099–2110. doi:10.1016/j.neubiorev.2012.05.009. PMID 22683929. 
  4. ^ Dalley, JW. "Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates". Retrieved 6 May 2011. 
  5. ^ Robinson, Emma SJ. "Similar Effects of the Selective Noradrenaline Reuptake". npb. Retrieved 6 May 2011. 
  6. ^ Zeeb, Fiona SJ. "Serotonergic and Dopaminergic Modulation of Gambling Behavior as Assessed Using a Novel Rat Gambling Task". npp. Retrieved 2 July 2014. 
  7. ^ Cocker,Hosking, Paul,Jay SJ. "Sensitivity to Cognitive Effort Mediates Psychostimulant Effects on a Novel Rodent Cost/Benefit Decision-Making Task". npp. Retrieved 2 July 2014.