|Centuries:||5th century – 6th century – 7th century|
|Decades:||510s 520s 530s – 540s – 550s 560s 570s|
|Years:||541 542 543 – 544 – 545 546 547|
|544 by topic|
|State leaders – Sovereign states|
|Birth and death categories|
|Births – Deaths|
|Establishment and disestablishment categories|
|Establishments – Disestablishments|
|Ab urbe condita||1297|
|Bahá'í calendar||−1300 – −1299|
|English Regnal year||N/A|
|Chinese calendar||癸亥年 (Water Pig)
3240 or 3180
— to —
甲子年 (Wood Rat)
3241 or 3181
|- Vikram Samvat||600–601|
|- Shaka Samvat||466–467|
|- Kali Yuga||3645–3646|
|Igbo calendar||−456 – −455|
|Iranian calendar||78 BP – 77 BP|
|Islamic calendar||80 BH – 79 BH|
|Minguo calendar||1368 before ROC
|Thai solar calendar||1087|
|Wikimedia Commons has media related to 544.|
Year 544 (DXLIV) was a leap year starting on Friday (link will display the full calendar) of the Julian calendar. The denomination 544 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years.
- Gothic War: Emperor Justinian I sends Belisarius back to Italy with an inadequate Byzantine expeditionary force (4,000 men and 200 ships) to once more fight the Ostrogoths.
- Belisarius defeats the Gothic army under king Totila who unsuccessfully besiege the city of Otranto (Southern Italy). After their retreat, the Byzantines march towards Rome.
- Justinian I issues a new edict condemning the Three Chapters. In Western Europe pope Vigilius refuses to acknowledge the imperial edict and is ordered to Constantinople.
- King Khosrau I unsuccessfully attacks the Byzantine fortress city of Dara. The siege of Edessa is repulsed and the Persians are forced into a stalemate.
- Battle of Cillium: A Byzantine army under Solomon is defeated by the Moors on the border of Numidia. Solomon and his bodyguard are forced to retreat and are later killed.
- February – Ly Bi is declared emperor and establish the empire Van Xuân (modern Vietnam). His armies repel attacks from the kingdom of Champa.
- October – The Liang Dynasty retaliates against Van Xuân and sends an imperial army (120,000 men) under Chen Baxian to re-occupy the region.
- Jacob Baradaeus consecrates Sergius of Tella as patriarch of Antioch, opening a permanent schism between the Syrian Orthodox Church and the Eastern Orthodox Church.
- Dugu Qieluo, empress of the Sui Dynasty (d. 602)
- Jing Di, emperor of the Liang Dynasty (d. 558)
- Yuwen Xian, prince of Northern Zhou (d. 578)
- Dionysius Exiguus, inventor of the Anno Domini era (approximate date)
- Solomon, Byzantine general and prefect of Africa
- October 18 – Wenna, Cornish Saint (approximate date)