6'-Guanidinonaltrindole

From Wikipedia, the free encyclopedia
Jump to: navigation, search
6'-Guanidinonaltrindole
6'-guanidinonaltrindole structure.png
Properties
Molecular formula C27H29N5O3
Molar mass 471.55 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

6'-Guanidinonaltrindole (6'-GNTI) is a κδ-opioid receptor selective ligand used in scientific research.[1] With 6'-GNTI, evidence was provided for the first time that receptor oligomizeration plays functional role in living organisms.[2]

See also[edit]

References[edit]

  1. ^ Rives ML, Rossillo M, Liu-Chen LY, Javitch JA (2012): J Biol Chem, 287(32):27050-4. PMID 22736766
  2. ^ Waldhoer M, Fong J, Jones RM, Lunzer MM, Sharma SK, Kostenis E, Portoghese PS, Whistler JL (June 2005). "A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers". Proc. Natl. Acad. Sci. U.S.A. 102 (25): 9050–5. doi:10.1073/pnas.0501112102. PMC 1157030. PMID 15932946.