6-CAT

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6-CAT
6-Chloro-2-aminotetralin.svg
Systematic (IUPAC) name
6-chloro-2-aminotetralin
Clinical data
Legal status Uncontrolled
Routes Oral
Identifiers
ATC code ?
ChemSpider 11269876 YesY
Chemical data
Formula ?
 N (what is this?)  (verify)

6-Chloro-2-aminotetralin (6-CAT) is a drug which acts as a selective serotonin releasing agent (SSRA) and is a putative entactogen in humans.[1][2] It is a rigid analogue of para-chloroamphetamine (PCA).[1]

According to Nichols et al.,[3] 6-CAT is a non-neurotoxic analog of PCA.

See also[edit]

References[edit]

  1. ^ a b Fuller RW, Perry KW, Baker JC, Molloy BB (November 1974). "6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats". Archives Internationales De Pharmacodynamie Et De Thérapie 212 (1): 141–53. PMID 4455127. 
  2. ^ Fuller, RW; Wong, DT; Snoddy, HD; Bymaster, FP (1977). "Comparison of the effects of 6-chloro-2-aminotetralin and of ORG 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats". Biochem. Pharmacol 26 (1): 1,333–1,337. 
  3. ^ Johnson, M. P.; Frescas, S. P.; Oberlender, R.; Nichols, D. E. (1991). "Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: Similarities to 3,4-(methylenedioxy)methamphetamine (MDMA)". Journal of Medical Chemistry 34 (5): 1662–1668. doi:10.1021/jm00109a020. PMID 1674539.  edit