8-Oxo-2'-deoxyguanosine

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8-Oxo-2'-deoxyguanosine
8-Oxo-2'-deoxyguanosine.svg
Identifiers
CAS number 88847-89-6
PubChem 73318
ChemSpider 66049 YesY
ChEBI CHEBI:40304
Jmol-3D images Image 1
Image 2
Properties
Molecular formula C10H13N5O5
Molar mass 283.24 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

8-Oxo-2'-deoxyguanosine (8-oxo-dG) is an oxidized derivative of deoxyguanosine. 8-oxo-dG is one of the major products of DNA oxidation.[1] Concentrations of 8-oxo-dG within a cell are a measurement of oxidative stress.

See also[edit]

References[edit]

  1. ^ Nadja C. de Souza-Pinto, Lars Eide, Barbara A. Hogue, Tanja Thybo, Tinna Stevnsner, Erling Seeberg, Arne Klungland, and Vilhelm A. Bohr (July 2001). "Repair of 8-Oxodeoxyguanosine Lesions in Mitochondrial DNA Depends on the Oxoguanine DNA Glycosylase (OGG1) Gene and 8-Oxoguanine Accumulates in the Mitochondrial DNA of OGG1-defective Mice". Cancer Research 61 (14): 5378–5381. PMID 11454679.