|Jmol-3D images||Image 1
|Molar mass||167.13 g mol−1|
| (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
8-Oxoguanine (8-hydroxyguanine, 8-oxo-Gua, or OH8Gua) is one of the most common DNA lesions resulting from reactive oxygen species  and can result in a mismatched pairing with Adenine resulting in G to T and A to C substitutions in the genome. In humans, it is primarily repaired by the DNA glycosylase OGG1. It can be caused by ionizing radiation, in connection with oxidative metabolism.
- 8-hydroxyguanine - Compound Summary, PubChem
- S. Kanvah, et al., Oxidation of DNA: Damage to Nucleobases; Acc. Chem. Res. 2010, 43(2), 280-287
- Cheng KC, Cahill DS, Kasai H, Nishimura S, Loeb LA (Jan 5, 1992). "8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G→T and A→C substitutions.". J Biol Chem. 267 (1): 166–72. PMID 1730583.