A-41988

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A-41988
A-41988.png
Systematic (IUPAC) name
8-[5-(4-fluorophenyl)pentan-2-yl]-5,5-dimethyl-2-prop-2-ynyl-3,4-dihydro-1H-chromeno[4,3-c]pyridin-10-ol
Clinical data
Legal status ?
Identifiers
CAS number 52763-30-1 YesY
ATC code ?
PubChem CID 3085018
ChemSpider 2341998 YesY
ChEMBL CHEMBL303312 YesY
Chemical data
Formula C28H32FNO2 
Mol. mass 433.556 g/mol
 YesY (what is this?)  (verify)

A-41988 (BW29Y) is an analgesic drug which acts as a cannabinoid agonist. It was developed by Abbott Laboratories in the 1970s,[1][2] and researched for potential use in the treatment of glaucoma,[3] but never commercialised.

See also[edit]

References[edit]

  1. ^ Winn, M.; Arendsen, D.; Dodge, P.; Dren, A.; Dunnigan, D.; Hallas, R.; Hwang, K.; Kyncl, J.; Lee, Y. H.; Plotnikoff, N.; Young, P.; Zaugg, H. (1976). "Drugs derived from cannabinoids. 5. Delta6a,10a-Tetrahydrocannabinol and heterocyclic analogs containing aromatic side chains". Journal of Medicinal Chemistry 19 (4): 461–471. doi:10.1021/jm00226a003. PMID 817021.  edit
  2. ^ Guterman A, Somani P, Bachand RT. Clinical Pharmacology and Therapeutics 1979; 25:227.
  3. ^ Tiedeman, J. S.; Shields, M. B.; Weber, P. A.; Crow, J. W.; Cocchetto, D. M.; Harris, W. A.; Howes, J. F. (1981). "Effect of synthetic cannabinoids on elevated intraocular pressure". Ophthalmology 88 (3): 270–277. doi:10.1016/s0161-6420(81)35052-0. PMID 7015221.  edit