Antipyrine and benzocaine ear drops

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Antipyrine and benzocaine ear drops is a medication for the treatment of ear pain caused by otitis media. It combines antipyrine, a pain reliever, benzocaine, a numbing agent to treat ear pain, and Hydroxyquinoline Sulfate, an antiseptic. It is sold as Auralgan, Aurodex, Auroto,[1] among other brands, and is abbreviated as A/B otic drops.


Each 1 ml of A/B otic drops contains:[2]

  • Antipyrine 54 mg
  • Benzocaine 14 mg
  • Glycerin and Hydroxyquinoline Sulfate USP


A/B otic drops is indicated for ear pain caused by otitis media. It is used every 2–3 hours as needed for pain.[2]

A/B otic drops is also indicated for the removal of excessive or impacted cerumen. To clear cerumen, it is used 3 times a day for 2–3 days.[2]

Clinical pharmacology[edit]

A/B otic drops are effective because antipyrine reduces pain and inflammation and benzocaine numbs the ear.


In 2008, Auralgan was reformulated to include acetic acid and U-polycosanol 410, in addition to antipyrine and benzocaine. Due to this reformulation, pharmacies could no longer substitute the generic antipyrine/benzocaine drops for a prescription written as "Auralgan". The price for the new formulation was roughly $150.00 compared to the generic price of $2.00.[3]


  2. ^ a b c "Auralgan (Antipyrine, Benzocaine, and Glygerin dehydrated) Drug information. Uses, side effects". Inc. Archived from the original on 25 October 2008. Retrieved 2008-11-10. 
  3. ^ "The new Auralgan is different from the older Auralgan". Retrieved 2012-06-16.