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ATP-binding cassette, sub-family G (WHITE), member 4
Symbols ABCG4 ; WHITE2
External IDs OMIM607784 MGI1890594 HomoloGene75179 IUPHAR: 793 GeneCards: ABCG4 Gene
RNA expression pattern
PBB GE ABCG4 207593 at tn.png
More reference expression data
Species Human Mouse
Entrez 64137 192663
Ensembl ENSG00000172350 ENSMUSG00000032131
UniProt Q9H172 Q91WA9
RefSeq (mRNA) NM_001142505 NM_138955
RefSeq (protein) NP_001135977 NP_620405
Location (UCSC) Chr 11:
119.02 – 119.03 Mb
Chr 9:
44.27 – 44.29 Mb
PubMed search [1] [2]

ATP-binding cassette sub-family G member 4 is a protein that in humans is encoded by the ABCG4 gene.[1][2]

The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.[2]

See also[edit]


  1. ^ Dean M, Rzhetsky A, Allikmets R (Jul 2001). "The human ATP-binding cassette (ABC) transporter superfamily". Genome Res 11 (7): 1156–66. doi:10.1101/gr.184901. PMID 11435397. 
  2. ^ a b "Entrez Gene: ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.