ABRA (gene)

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Actin-binding Rho activating protein
Identifiers
Symbols ABRA ; STARS
External IDs OMIM609747 MGI2444891 HomoloGene34713 GeneCards: ABRA Gene
RNA expression pattern
PBB GE ABRA gnf1h08948 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 137735 223513
Ensembl ENSG00000174429 ENSMUSG00000042895
UniProt Q8N0Z2 Q8BUZ1
RefSeq (mRNA) NM_139166 NM_175456
RefSeq (protein) NP_631905 NP_780665
Location (UCSC) Chr 8:
107.77 – 107.78 Mb
Chr 15:
41.87 – 41.87 Mb
PubMed search [1] [2]

Actin-binding Rho-activating protein is a protein that in humans is encoded by the ABRA gene.[1] The mouse and rat homologues are known as STARS (striated muscle activator of Rho signalling) and MS1 (myocyte stress 1) respectively.[2]


MS1/STARS is regulated by MyoD during myogenic differentiation of the C2C12 cell line.

References[edit]

  1. ^ Arai A, Spencer JA, Olson EN (Jul 2002). "STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription". J Biol Chem 277 (27): 24453–9. doi:10.1074/jbc.M202216200. PMID 11983702. 
  2. ^ "Entrez Gene: ABRA actin-binding Rho activating protein". 

Further reading[edit]