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Acetyl-CoA acetyltransferase 2
PDB 1wl4 EBI.png
PDB rendering based on 1wl4.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbol ACAT2
External IDs OMIM100678 MGI109182 HomoloGene55855 IUPHAR: 2436 ChEMBL: 2240 GeneCards: ACAT2 Gene
EC number
Species Human Mouse
Entrez 39 110460
Ensembl ENSG00000120437 ENSMUSG00000023832
UniProt Q9BWD1 Q8CAY6
RefSeq (mRNA) NM_005891 NM_009338.3
RefSeq (protein) NP_005882 NP_033364.2
Location (UCSC) Chr 6:
160.18 – 160.2 Mb
Chr 17:
13.14 – 13.15 Mb
PubMed search [1] [2]

Acetyl-CoA acetyltransferase, cytosolic, also known as cytosolic acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT2 (acetyl-Coenzyme A acetyltransferase 2) gene[1]

Acetyl-Coenzyme A acetyltransferase 2 is an acetyl-CoA C-acetyltransferase enzyme.


This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.[1]


Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.