ACTR2

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ARP2 actin-related protein 2 homolog (yeast)
Protein ACTR2 PDB 1k8k.png
PDB rendering based on 1k8k.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ACTR2 ; ARP2
External IDs OMIM604221 MGI1913963 HomoloGene4181 ChEMBL: 6090 GeneCards: ACTR2 Gene
Orthologs
Species Human Mouse
Entrez 10097 66713
Ensembl ENSG00000138071 ENSMUSG00000020152
UniProt P61160 P61161
RefSeq (mRNA) NM_001005386 NM_146243
RefSeq (protein) NP_001005386 NP_666355
Location (UCSC) Chr 2:
65.45 – 65.5 Mb
Chr 11:
20.06 – 20.11 Mb
PubMed search [1] [2]

Actin-related protein 2 is a protein that in humans is encoded by the ACTR2 gene.[1]

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.[2]

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