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Adenosine deaminase, RNA-specific, B2 (non-functional)
Symbols ADARB2 ; ADAR3; RED2
External IDs OMIM602065 MGI2151118 HomoloGene10276 GeneCards: ADARB2 Gene
RNA expression pattern
PBB GE ADARB2 220648 at tn.png
More reference expression data
Species Human Mouse
Entrez 105 94191
Ensembl ENSG00000185736 ENSMUSG00000052551
UniProt Q9NS39 Q9JI20
RefSeq (mRNA) NM_018702 NM_001289530
RefSeq (protein) NP_061172 NP_001276459
Location (UCSC) Chr 10:
1.23 – 1.78 Mb
Chr 13:
8.2 – 8.77 Mb
PubMed search [1] [2]

Double-stranded RNA-specific editase B2 is an enzyme that in humans is encoded by the ADARB2 gene.[1][2][3]

RNA-editing deaminase-2 (RED2, or ADARB2) is a member of the double-stranded RNA (dsRNA) adenosine deaminase family of RNA-editing enzymes. Adenosine deamination of pre-mRNA results in a change in the amino acid sequence of the gene product, which differs from that predicted by the genomic DNA sequence. Other members of this family include DRADA (ADAR; MIM 601059) and RED1 (ADARB1; MIM 601218) (Mittaz et al., 1997 [PubMed 9272162]).[supplied by OMIM][3]


  1. ^ Mittaz L, Antonarakis SE, Higuchi M, Scott HS (Sep 1997). "Localization of a novel human RNA-editing deaminase (hRED2 or ADARB2) to chromosome 10p15". Hum Genet 100 (3–4): 398–400. doi:10.1007/s004390050523. PMID 9272162. 
  2. ^ Chen CX, Cho DS, Wang Q, Lai F, Carter KC, Nishikura K (Jun 2000). "A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains". RNA 6 (5): 755–67. doi:10.1017/S1355838200000170. PMC 1369955. PMID 10836796. 
  3. ^ a b "Entrez Gene: ADARB2 adenosine deaminase, RNA-specific, B2 (RED2 homolog rat)". 

Further reading[edit]