ADCY7

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Adenylate cyclase 7
Identifiers
Symbols ADCY7 ; AC7
External IDs OMIM600385 MGI102891 HomoloGene866 ChEMBL: 4922 GeneCards: ADCY7 Gene
EC number 4.6.1.1
RNA expression pattern
PBB GE ADCY7 203741 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 113 11513
Ensembl ENSG00000121281 ENSMUSG00000031659
UniProt P51828 P51829
RefSeq (mRNA) NM_001114 NM_001037723
RefSeq (protein) NP_001105 NP_001032812
Location (UCSC) Chr 16:
50.28 – 50.35 Mb
Chr 8:
88.27 – 88.33 Mb
PubMed search [1] [2]

Adenylate cyclase type 7 is an enzyme that in humans is encoded by the ADCY7 gene.[1][2]

Function[edit]

This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences.[2]

References[edit]

  1. ^ Hellevuo K, Berry R, Sikela JM, Tabakoff B (Mar 1995). "Localization of the gene for a novel human adenylyl cyclase (ADCY7) to chromosome 16". Hum Genet 95 (2): 197–200. doi:10.1007/bf00209401. PMID 7860067. 
  2. ^ a b "Entrez Gene: ADCY7 adenylate cyclase 7". 

Further reading[edit]