ADP—thymidine kinase

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ADP-thymidine kinase
Identifiers
EC number 2.7.1.118
CAS number 82114-39-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an ADP—thymidine kinase (EC 2.7.1.118) is an enzyme that catalyzes the chemical reaction

ADP + thymidine \rightleftharpoons AMP + thymidine 5'-phosphate

Thus, the two substrates of this enzyme are ADP and thymidine, whereas its two products are AMP and thymidine 5'-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ADP:thymidine 5'-phosphotransferase. Other names in common use include ADP:dThd phosphotransferase, and adenosine diphosphate-thymidine phosphotransferase.

References[edit]

  • Falke D, Labenz J, Brauer D, Muller WE (1982). "Adenosine diphosphate: thymidine 5'-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase". Biochim. Biophys. Acta. 708 (1): 99–103. doi:10.1016/0167-4838(82)90207-2. PMID 6293576.