AHCYL1
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| Adenosylhomocysteinase-like 1 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | AHCYL1; DCAL; IRBIT; PRO0233; XPVKONA | ||||||||||||
| External IDs | OMIM: 607826 MGI: 2385184 HomoloGene: 77353 GeneCards: AHCYL1 Gene | ||||||||||||
| EC number | 3.3.1.1 | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10768 | 229709 | |||||||||||
| Ensembl | ENSG00000168710 | ENSMUSG00000027893 | |||||||||||
| UniProt | O43865 | Q80SW1 | |||||||||||
| RefSeq (mRNA) | NM_001242673.1 | NM_145542.3 | |||||||||||
| RefSeq (protein) | NP_001229602.1 | NP_663517.2 | |||||||||||
| Location (UCSC) | Chr 1: 110.53 – 110.57 Mb |
Chr 3: 107.47 – 107.5 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Putative adenosylhomocysteinase 2 is an enzyme that in humans is encoded by the AHCYL1 gene.[1][2][3][4]
[edit] Interactions
AHCYL1 has been shown to interact with ITPR1.[3]
[edit] References
- ^ Dekker JW, Budhia S, Angel NZ, Cooper BJ, Clark GJ, Hart DN, Kato M (Mar 2002). "Identification of an S-adenosylhomocysteine hydrolase-like transcript induced during dendritic cell differentiation". Immunogenetics 53 (12): 993–1001. doi:10.1007/s00251-001-0402-z. PMID 11904675.
- ^ Cooper BJ, Key B, Carter A, Angel NZ, Hart DN, Kato M (Aug 2006). "Suppression and overexpression of adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) influences zebrafish embryo development: a possible role for AHCYL1 in inositol phospholipid signaling". J Biol Chem 281 (32): 22471–84. doi:10.1074/jbc.M602520200. PMID 16754674.
- ^ a b Ando H, Mizutani A, Matsu-ura T, Mikoshiba K (Mar 2003). "IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor". J Biol Chem 278 (12): 10602–12. doi:10.1074/jbc.M210119200. PMID 12525476.
- ^ "Entrez Gene: AHCYL1 S-adenosylhomocysteine hydrolase-like 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10768.
[edit] Further reading
- Pawlak A, Toussaint C, Lévy I, et al. (1995). "Characterization of a large population of mRNAs from human testis.". Genomics 26 (1): 151–8. doi:10.1016/0888-7543(95)80096-5. PMID 7782076.
- Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
- Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139146.
- Cleaver JE, Afzal V, Feeney L, et al. (1999). "Increased ultraviolet sensitivity and chromosomal instability related to P53 function in the xeroderma pigmentosum variant.". Cancer Res. 59 (5): 1102–8. PMID 10070969.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Imabayashi H, Mori T, Gojo S, et al. (2003). "Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis.". Exp. Cell Res. 288 (1): 35–50. doi:10.1016/S0014-4827(03)00130-7. PMID 12878157.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.". Mol. Cell Proteomics 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Shirakabe K, Priori G, Yamada H, et al. (2006). "IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/HCO3- cotransporter 1 (pNBC1).". Proc. Natl. Acad. Sci. U.S.A. 103 (25): 9542–7. doi:10.1073/pnas.0602250103. PMC 1480443. PMID 16769890. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1480443.
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