AL-LAD

From Wikipedia, the free encyclopedia
Jump to: navigation, search
AL-LAD
AL-LAD structure.svg
Systematic (IUPAC) name
6-Allyl-6-nor-lysergic acid diethylamide
Clinical data
Legal status
Identifiers
CAS number 65527-61-9 N
ATC code ?
PubChem CID 15227511
ChemSpider 21106248 YesY
ChEMBL CHEMBL281787 YesY
Chemical data
Formula C22H27N3O 
Mol. mass 349.4713
 N (what is this?)  (verify)

AL-LAD, also known as 6-allyl-6-nor-LSD, is a designer psychedelic drug and an analog of lysergic acid diethylamide (LSD). It is described by Alexander Shulgin in the book TiHKAL (Tryptamines i Have Known And Loved).

Effects in humans[edit]

AL-LAD on blotter paper

While AL-LAD has subtly different effects than LSD, and appears to be slightly shorter lasting, their potencies are similar;[1] an active dose of AL-LAD is reported to be between 80 and 160 micrograms.[2]

Chemistry[edit]

AL-LAD does not cause a color change with the Marquis, Mecke or Mandelin reagents,[3] but does cause the Ehrlich's reagent to turn purple because of the presence of the indole moiety in its structure.

Legal status[edit]

On June 10th 2014 the UK Advisory Council on the Misuse of Drugs (ACMD) recommended that AL-LAD be specifically named in the UK Misuse of Drugs Act as a class A drug despite not identifying any harm associated with its use.[4]

See also[edit]

References[edit]

  1. ^ Hoffman AJ, Nichols DE; Nichols (September 1985). "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives". Journal of Medicinal Chemistry 28 (9): 1252–5. doi:10.1021/jm00147a022. PMID 4032428. 
  2. ^ Shulgin, Alexander; Ann Shulgin (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press, 392. ISBN 0-9630096-9-9. OCLC 38503252. 
  3. ^ Ecstasydata. "EcstasyData.org - AL-LAD (Not sold as ecstasy)". Retrieved 2013-12-25. 
  4. ^ ACMD (10 June 2014). "Update of the Generic Definition for Tryptamines". UK Home Office. p. 12. Retrieved 10 June 2014. 

Additional literature[edit]

  • Hoffman, Andrew J.; Nichols, David E. (1985). "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives". Journal of Medicinal Chemistry 28 (9): 1252–5. doi:10.1021/jm00147a022. PMID 4032428. 
  • Watts, V. J.; Mailman, R. B.; Lawler, C. P.; Neve, K. A.; Nichols, D. E. (1995). "LSD and structural analogs: Pharmacological evaluation at D1 dopamine receptors". Psychopharmacology 118 (4): 401–9. doi:10.1007/BF02245940. PMID 7568626. 
  • Niwaguchi, T; Nakahara, Y; Ishii, H (1976). "Studies on lysergic acid diethylamide and related compounds. IV. Syntheses of various amide derivatives of norlysergic acid and related compounds". Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 96 (5): 673–8. PMID 987200. 
  • Robert C. Pfaff, Xuemei Huang, Danuta Marona-Lewicka, Robert Oberlender and David E. Nichols: Lysergamides Revisited. In: NIDA Research Monograph 146: Hallucinogens: An Update. p. 52, 1994, United States Department of Health and Human Services.

External links[edit]