AL-LAD

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AL-LAD
AL-LAD structure.svg
Systematic (IUPAC) name
6-allyl-6-nor-lysergic acid diethylamide
Clinical data
Legal status Legal (CA) Legal (UK) Controlled in the United States via the Federal Analog Act (US)
Identifiers
CAS number 65527-61-9 N
ATC code ?
PubChem CID 15227511
ChemSpider 21106248 YesY
ChEMBL CHEMBL281787 YesY
Chemical data
Formula C22H27N3O 
Mol. mass 349.4713
 N (what is this?)  (verify)

AL-LAD, also known as 6-allyl-6-nor-LSD, is a novel psychedelic drug and an analogue of LSD. It is described by Alexander Shulgin in the book TiHKAL (Tryptamines i Have Known And Loved). AL-LAD does not cause a colour change with the marquis, mecke or mandelin reagents[1] but does cause the ehrlich's reagent to turn purple because of the presence of the indole moiety in its structure.


Effects in humans[edit]

AL-LAD on blotter paper

While AL-LAD has subtly different effects than LSD, and appears to be slightly shorter lasting, their potencies are similar;[2] an active dose of AL-LAD is reported to be between 80 and 160 micrograms[3] though there are many reports of higher dosages being taken.[4]

Legal Status[edit]

On June 10th 2014 the UK ACMD recommended that AL-LAD be specifically named in the UK Misuse of Drugs Act as a class A drug despite not identifying any harm associated with its use.[5]

Literature[edit]

  • Andrew J. Hoffman, David E. Nichols: Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives. In: Journal of Medicinal Chemistry. 28, 1985, p. 1252–1255, doi:10.1021/jm00147a022.
  • V. J. Watts, R. B. Mailman, C. P. Lawler, K. A. Neve, D. E. Nichols: LSD and structural analogs: pharmacological evaluation at D1 dopamine receptors. In: Psychopharmacology. 118, 1995, p. 401–409, doi:10.1007/BF02245940.
  • T. Niwaguchi, Y. Nakahara, H. Ishii: Studies on lysergic acid diethylamide and related compounds. IV. Syntheses of various amide derivatives of norlysergic acid and related compounds. In: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. Vol. 96, No. 5, May 1976, p. 673–678, PMID 987200.
  • Robert C. Pfaff, Xuemei Huang, Danuta Marona-Lewicka, Robert Oberlender and David E. Nichols: Lysergamides Revisited. In: NIDA Research Monograph 146: Hallucinogens: An Update. p. 52, 1994, United States Department of Health and Human Services.

See also[edit]

References[edit]

  1. ^ Ecstasydata. "EcstasyData.org - AL-LAD (Not sold as ecstasy)". Retrieved 2013-12-25. 
  2. ^ Hoffman AJ, Nichols DE (September 1985). "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives". Journal of Medicinal Chemistry 28 (9): 1252–5. doi:10.1021/jm00147a022. PMID 4032428. 
  3. ^ Shulgin, Alexander; Ann Shulgin (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press, 392. ISBN 0-9630096-9-9. OCLC 38503252. 
  4. ^ "AL-LAD Thread. UKChemicalResearch.org". 
  5. ^ ACMD (10 June 2014). "Update of the Generic Definition for Tryptamines". UK Home Office. p. 12. Retrieved 10 June 2014. 

External links[edit]