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Amylase, alpha 2B (pancreatic)
Protein AMY2B PDB 1b2y.png
PDB rendering based on 1b2y.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols AMY2B ; AMY2; AMY3; HXA
External IDs OMIM104660 HomoloGene134663 ChEMBL: 2477 GeneCards: AMY2B Gene
EC number
RNA expression pattern
PBB GE AMY2B 208498 s at tn.png
More reference expression data
Species Human Mouse
Entrez 280 109959
Ensembl ENSG00000240038 ENSMUSG00000074268
UniProt P19961 P00688
RefSeq (mRNA) NM_020978 NM_001042711
RefSeq (protein) NP_066188 NP_001036176
Location (UCSC) Chr 1:
104.1 – 104.12 Mb
Chr 3:
113.25 – 113.26 Mb
PubMed search [1] [2]

Alpha-amylase 2B is an enzyme that in humans is encoded by the AMY2B gene.[1][2]

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.[2]


  1. ^ Omichi K, Hase S (Jan 1994). "Identification of the characteristic amino-acid sequence for human alpha-amylase encoded by the AMY2B gene". Biochim Biophys Acta 1203 (2): 224–9. doi:10.1016/0167-4838(93)90087-8. PMID 8268204. 
  2. ^ a b "Entrez Gene: AMY2B amylase, alpha 2B (pancreatic)". 

Further reading[edit]