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Ankyrin repeat domain 23
Symbols ANKRD23 ; DARP; MARP3
External IDs OMIM610736 MGI1925571 HomoloGene14025 GeneCards: ANKRD23 Gene
Species Human Mouse
Entrez 200539 78321
Ensembl ENSG00000163126 ENSMUSG00000067653
UniProt Q86SG2 Q812A3
RefSeq (mRNA) NM_144994 NM_153502
RefSeq (protein) NP_659431 NP_705722
Location (UCSC) Chr 2:
97.49 – 97.52 Mb
Chr 1:
36.53 – 36.54 Mb
PubMed search [1] [2]

Ankyrin repeat domain-containing protein 23 is a protein that in humans is encoded by the ANKRD23 gene.[1][2]

This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem ankyrin-like repeats. The protein is localized to the nucleus, functioning as a transcriptional regulator. Expression of this protein is induced during recovery following starvation.[2]


ANKRD23 has been shown to interact with Titin[3] and MYPN.[3]


  1. ^ Ikeda K, Emoto N, Matsuo M, Yokoyama M (Feb 2003). "Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals". J Biol Chem 278 (6): 3514–20. doi:10.1074/jbc.M204563200. PMID 12456686. 
  2. ^ a b "Entrez Gene: ANKRD23 ankyrin repeat domain 23". 
  3. ^ a b Miller, Melanie K; Bang Marie-Louise; Witt Christian C; Labeit Dietmar; Trombitas Charles; Watanabe Kaori; Granzier Henk; McElhinny Abigail S; Gregorio Carol C; Labeit Siegfried (Nov 2003). "The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules". J. Mol. Biol. (England) 333 (5): 951–64. doi:10.1016/j.jmb.2003.09.012. ISSN 0022-2836. PMID 14583192. 

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