AP1M2

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Adaptor-related protein complex 1, mu 2 subunit
Identifiers
Symbols AP1M2 ; AP1-mu2; HSMU1B; MU-1B; MU1B; mu2
External IDs OMIM607309 MGI1336974 HomoloGene55906 GeneCards: AP1M2 Gene
RNA expression pattern
PBB GE AP1M2 65517 at tn.png
PBB GE AP1M2 218261 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10053 11768
Ensembl ENSG00000129354 ENSMUSG00000003309
UniProt Q9Y6Q5 Q9WVP1
RefSeq (mRNA) NM_001300887 NM_001110300
RefSeq (protein) NP_001287816 NP_001103770
Location (UCSC) Chr 19:
10.68 – 10.7 Mb
Chr 9:
21.3 – 21.31 Mb
PubMed search [1] [2]

AP-1 complex subunit mu-2 is a protein that in humans is encoded by the AP1M2 gene.[1][2]

This gene encodes a subunit of the heterotetrameric adaptor-related protein complex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals.[2]

Interactions[edit]

AP1M2 has been shown to interact with AP2B1.[3]

References[edit]

  1. ^ Ohno H, Tomemori T, Nakatsu F, Okazaki Y, Aguilar RC, Foelsch H, Mellman I, Saito T, Shirasawa T, Bonifacino JS (June 1999). "Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells". FEBS Lett 449 (2–3): 215–20. doi:10.1016/S0014-5793(99)00432-9. PMID 10338135. 
  2. ^ a b "Entrez Gene: AP1M2 adaptor-related protein complex 1, mu 2 subunit". 
  3. ^ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

Further reading[edit]

External links[edit]