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Adaptor-related protein complex 3, delta 1 subunit
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols AP3D1 ; ADTD; hBLVR
External IDs OMIM607246 MGI107734 HomoloGene2926 GeneCards: AP3D1 Gene
RNA expression pattern
PBB GE AP3D1 206592 s at tn.png
PBB GE AP3D1 210974 s at tn.png
PBB GE AP3D1 208710 s at tn.png
More reference expression data
Species Human Mouse
Entrez 8943 11776
Ensembl ENSG00000065000 ENSMUSG00000020198
UniProt O14617 O54774
RefSeq (mRNA) NM_001077523 NM_007460
RefSeq (protein) NP_001248755 NP_031486
Location (UCSC) Chr 19:
2.1 – 2.16 Mb
Chr 10:
80.71 – 80.74 Mb
PubMed search [1] [2]

AP-3 complex subunit delta-1 is a protein that in humans is encoded by the AP3D1 gene.[1][2][3]


AP3D1 is a subunit of the AP3 adaptor-like complex, which is not associated with clathrin. The AP3D1 subunit is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.[supplied by OMIM][3]


AP3D1 has been shown to interact with SYBL1.[4]


  1. ^ Simpson F, Peden AA, Christopoulou L, Robinson MS (May 1997). "Characterization of the adaptor-related protein complex, AP-3". The Journal of Cell Biology 137 (4): 835–45. doi:10.1083/jcb.137.4.835. PMC 2139840. PMID 9151686. 
  2. ^ Ooi CE, Moreira JE, Dell'Angelica EC, Poy G, Wassarman DA, Bonifacino JS (Aug 1997). "Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet". The EMBO Journal 16 (15): 4508–18. doi:10.1093/emboj/16.15.4508. PMC 1170077. PMID 9303295. 
  3. ^ a b "Entrez Gene: AP3D1 adaptor-related protein complex 3, delta 1 subunit". 
  4. ^ Martinez-Arca S, Rudge R, Vacca M, Raposo G, Camonis J, Proux-Gillardeaux V et al. (Jul 2003). "A dual mechanism controlling the localization and function of exocytic v-SNAREs". Proceedings of the National Academy of Sciences of the United States of America 100 (15): 9011–6. doi:10.1073/pnas.1431910100. PMC 166429. PMID 12853575. 

Further reading[edit]