APC internal ribosome entry site (IRES)
|APC internal ribosome entry site (IRES)|
|Predicted secondary structure and sequence conservation of IRES_APC|
|RNA type||Cis-reg; IRES|
The APC internal ribosome entry site (IRES) is an RNA element which is located in the coding sequence of the APC gene. APC is a tumour suppressor gene which is associated with the inherited disease adenomatous polyposis coli (APC). It is thought that IRES-mediated translation of APC is important for an apoptotic cascade.
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