APOA1BP

From Wikipedia, the free encyclopedia
Jump to: navigation, search
apolipoprotein A-I-binding protein
Identifiers
Symbol APOA1BP
Entrez 128240
HUGO 18453
OMIM 608862
RefSeq NM_144772
UniProt Q8NCW5
Other data
Locus Chr. 1 q21

Apolipoprotein A-I-binding protein also known as APOA1BP is a protein that in humans is encoded by the APOA1BP gene.[1]

Function[edit]

APOA1BP binds to APOA1, APOA2, and high-density lipoprotein (HDL).[1] In addition, APOA1BP appears to play a role in sperm capacitation.[2]

References[edit]

  1. ^ a b Ritter M, Buechler C, Boettcher A, Barlage S, Schmitz-Madry A, Orsó E, Bared SM, Schmiedeknecht G, Baehr CH, Fricker G, Schmitz G (May 2002). "Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I". Genomics 79 (5): 693–702. doi:10.1006/geno.2002.6761. PMID 11991719. 
  2. ^ Jha KN, Shumilin IA, Digilio LC, Chertihin O, Zheng H, Schmitz G, Visconti PE, Flickinger CJ, Minor W, Herr JC (May 2008). "Biochemical and Structural Characterization of Apolipoprotein A-I Binding Protein, a Novel Phosphoprotein with a Potential Role in Sperm Capacitation". Endocrinology 149 (5): 2108–20. doi:10.1210/en.2007-0582. PMC 2329272. PMID 18202122.