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Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols APOBEC3C ; A3C; APOBEC1L; ARDC2; ARDC4; ARP5; PBI; bK150C2.3
External IDs OMIM607750 HomoloGene129856 GeneCards: APOBEC3C Gene
EC number 3.5.4.-
Species Human Mouse
Entrez 27350 n/a
Ensembl ENSG00000244509 n/a
UniProt Q9NRW3 n/a
RefSeq (mRNA) NM_014508 n/a
RefSeq (protein) NP_055323 n/a
Location (UCSC) Chr 22:
39.41 – 39.42 Mb
PubMed search [1] n/a

Probable DNA dC->dU-editing enzyme APOBEC-3C is a protein that in humans is encoded by the APOBEC3C gene.[1][2]

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.[2]


  1. ^ Jarmuz A, Chester A, Bayliss J, Gisbourne J, Dunham I, Scott J, Navaratnam N (Feb 2002). "An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22". Genomics 79 (3): 285–96. doi:10.1006/geno.2002.6718. PMID 11863358. 
  2. ^ a b "Entrez Gene: APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C". 

Further reading[edit]