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Apolipoprotein L, 3
Symbols APOL3 ; APOLIII; CG121
External IDs OMIM607253 MGI1923011 HomoloGene129701 GeneCards: APOL3 Gene
RNA expression pattern
PBB GE APOL3 221087 s at tn.png
More reference expression data
Species Human Mouse
Entrez 80833 75761
Ensembl ENSG00000128284 ENSMUSG00000010601
UniProt O95236 B2RT54
RefSeq (mRNA) NM_014349 NM_001164640
RefSeq (protein) NP_663615 NP_001158112
Location (UCSC) Chr 22:
36.54 – 36.56 Mb
Chr 15:
77.39 – 77.4 Mb
PubMed search [1] [2]

Apolipoprotein L3 is a protein that in humans is encoded by the APOL3 gene.[1][2]

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. In addition, expression of this gene is upregulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery[disambiguation needed] and aorta. Six transcript variants encoding three different isoforms have been found for this gene.[2]


  1. ^ Page NM, Butlin DJ, Lomthaisong K, Lowry PJ (May 2001). "The human apolipoprotein L gene cluster: identification, classification, and sites of distribution". Genomics 74 (1): 71–8. doi:10.1006/geno.2001.6534. PMID 11374903. 
  2. ^ a b "Entrez Gene: APOL3 apolipoprotein L, 3". 

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