AQP5

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Aquaporin 5
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols AQP5 ; AQP-5
External IDs OMIM600442 MGI106215 HomoloGene20398 IUPHAR: AQP5 GeneCards: AQP5 Gene
RNA expression pattern
PBB GE AQP5 213611 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 362 11830
Ensembl ENSG00000161798 ENSMUSG00000044217
UniProt P55064 Q9WTY4
RefSeq (mRNA) NM_001651 NM_009701
RefSeq (protein) NP_001642 NP_033831
Location (UCSC) Chr 12:
50.36 – 50.36 Mb
Chr 15:
99.59 – 99.59 Mb
PubMed search [1] [2]

Aquaporin-5 is a protein that in humans is encoded by the AQP5 gene.[1][2]

Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.[2]

See also[edit]

References[edit]

  1. ^ Lee MD, Bhakta KY, Raina S, Yonescu R, Griffin CA, Copeland NG, Gilbert DJ, Jenkins NA, Preston GM, Agre P (Jun 1996). "The human Aquaporin-5 gene. Molecular characterization and chromosomal localization". J Biol Chem 271 (15): 8599–604. doi:10.1074/jbc.271.15.8599. PMID 8621489. 
  2. ^ a b "Entrez Gene: AQP5 aquaporin 5". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.