ARHGAP4

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Rho GTPase activating protein 4
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ARHGAP4 ; C1; RGC1; RhoGAP4; SrGAP4; p115
External IDs OMIM300023 MGI2159577 HomoloGene20403 GeneCards: ARHGAP4 Gene
RNA expression pattern
PBB GE ARHGAP4 204425 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 393 171207
Ensembl ENSG00000089820 ENSMUSG00000031389
UniProt P98171 Q80Z68
RefSeq (mRNA) NM_001164741 NM_001162423
RefSeq (protein) NP_001158213 NP_001155895
Location (UCSC) Chr HG1497_PATCH:
153.11 – 153.14 Mb
Chr X:
73.89 – 73.92 Mb
PubMed search [1] [2]

Rho GTPase-activating protein 4 is an enzyme that in humans is encoded by the ARHGAP4 gene.[1][2] It has been shown to regulate cell motility and axonal outgrowth in vitro.[3]


References[edit]

  1. ^ Tribioli C, Droetto S, Bione S, Cesareni G, Torrisi MR, Lotti LV, Lanfrancone L, Toniolo D, Pelicci P (Mar 1996). "An X chromosome-linked gene encoding a protein with characteristics of a rhoGAP predominantly expressed in hematopoietic cells". Proc Natl Acad Sci U S A 93 (2): 695–9. doi:10.1073/pnas.93.2.695. PMC 40115. PMID 8570618. 
  2. ^ "Entrez Gene: ARHGAP4 Rho GTPase activating protein 4". 
  3. ^ Vogt, DL; Gray, CD; Young Ws, 3rd; Orellana, SA; Malouf, AT (2007). "ARHGAP4 IS A NOVEL RHOGAP THAT MEDIATES INHIBITION OF CELL MOTILITY AND AXON OUTGROWTH". Molecular and cellular neurosciences 36 (3): 332–42. doi:10.1016/j.mcn.2007.07.004. PMC 2111057. PMID 17804252. 

Further reading[edit]