Rho guanine nucleotide exchange factor 9 is a protein that in humans is encoded by the ARHGEF9gene.
ARHGEF9 belongs to a family of Rho-like GTPases that act as molecular switches by cycling from the active GTP-bound state to the inactive GDP-bound state. These proteins are key regulators of the actin cytoskeleton and are involved in cell signaling.[supplied by OMIM]
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