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Ankyrin repeat and SOCS box containing 6
Symbols ASB6 ; FLJ20548; MGC1024
External IDs OMIM615051 MGI1919573 HomoloGene9895 GeneCards: ASB6 Gene
RNA expression pattern
PBB GE ASB6 221657 s at tn.png
More reference expression data
Species Human Mouse
Entrez 140459 72323
Ensembl ENSG00000148331 ENSMUSG00000039483
UniProt Q9NWX5 Q91ZU1
RefSeq (mRNA) NM_001202403 NM_133346
RefSeq (protein) NP_001189332 NP_579924
Location (UCSC) Chr 9:
132.4 – 132.4 Mb
Chr 2:
30.82 – 30.83 Mb
PubMed search [1] [2]

Ankyrin repeat and SOCS box protein 6 is a protein that in humans is encoded by the ASB6 gene.[1]

The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases.[1]


Further reading[edit]