ATG7

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Autophagy related 7
Identifiers
Symbols ATG7 ; APG7-LIKE; APG7L; GSA7
External IDs OMIM608760 MGI1921494 HomoloGene4662 GeneCards: ATG7 Gene
RNA expression pattern
PBB GE ATG7 218673 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10533 74244
Ensembl ENSG00000197548 ENSMUSG00000030314
UniProt O95352 Q9D906
RefSeq (mRNA) NM_001136031 NM_001253717
RefSeq (protein) NP_001129503 NP_001240646
Location (UCSC) Chr 3:
11.31 – 11.6 Mb
Chr 6:
114.64 – 114.86 Mb
PubMed search [1] [2]

Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene.[1][2]

This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vaculuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.[2]

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