ATL-444

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ATL-444
ATL-444 structure.png
Systematic (IUPAC) name
(1S,3R)-1-[2-(6-amino-9-prop-2-ynylpurin-2-yl)ethynyl]-3-methylcyclohexan-1-ol
Clinical data
Legal status ?
Identifiers
ATC code ?
PubChem CID 11616539
ChemSpider 9791288
Chemical data
Formula C17H19N5O 
Mol. mass 309.365 g/mol

ATL-444 is a drug which acts as a potent and reasonably selective antagonist for the adenosine receptors A1 and A2A. It has been used to study the role of the adenosine receptor system in the reinforcing action of cocaine.[1]

See also[edit]

References[edit]

  1. ^ Doyle, S. E.; Breslin, F. J.; Rieger, J. M.; Beauglehole, A.; Lynch, W. J. (2012). "Time and sex-dependent effects of an adenosine A2A/A1 receptor antagonist on motivation to self-administer cocaine in rats". Pharmacology Biochemistry and Behavior 102 (2): 257–263. doi:10.1016/j.pbb.2012.05.001. PMC 3383440. PMID 22579716.  edit