ATP synthase subunit delta, mitochondrial is an enzyme that in humans is encoded by the ATP5Dgene.
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the delta subunit of the catalytic core. Alternatively spliced transcript variants encoding the same isoform have been identified.
^Jordan EM, Breen GA (Apr 1992). "Molecular cloning of an import precursor of the delta-subunit of the human mitochondrial ATP synthase complex". Biochim Biophys Acta1130 (1): 123–6. doi:10.1016/0167-4781(92)90477-h. PMID1531933.
Yoshida M, Muneyuki E, Hisabori T (2001). "ATP synthase--a marvellous rotary engine of the cell". Nat. Rev. Mol. Cell Biol.2 (9): 669–77. doi:10.1038/35089509. PMID11533724.
Hochstrasser DF, Frutiger S, Paquet N et al. (1993). "Human liver protein map: a reference database established by microsequencing and gel comparison". Electrophoresis13 (12): 992–1001. doi:10.1002/elps.11501301201. PMID1286669.