ATP5D

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ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
Protein ATP5D PDB 1e79.png
PDB rendering based on 1e79.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbol ATP5D
External IDs OMIM603150 MGI1913293 HomoloGene37514 GeneCards: ATP5D Gene
EC number 3.6.1.14
RNA expression pattern
PBB GE ATP5D 213041 s at tn.png
PBB GE ATP5D 203926 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 513 66043
Ensembl ENSG00000099624 ENSMUSG00000003072
UniProt P30049 Q9D3D9
RefSeq (mRNA) NM_001001975 NM_025313
RefSeq (protein) NP_001001975 NP_079589
Location (UCSC) Chr 19:
1.24 – 1.24 Mb
Chr 10:
80.14 – 80.15 Mb
PubMed search [1] [2]

ATP synthase subunit delta, mitochondrial is an enzyme that in humans is encoded by the ATP5D gene.[1][2]

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the delta subunit of the catalytic core. Alternatively spliced transcript variants encoding the same isoform have been identified.[2]

References[edit]

  1. ^ Jordan EM, Breen GA (Apr 1992). "Molecular cloning of an import precursor of the delta-subunit of the human mitochondrial ATP synthase complex". Biochim Biophys Acta 1130 (1): 123–6. doi:10.1016/0167-4781(92)90477-h. PMID 1531933. 
  2. ^ a b "Entrez Gene: ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit". 

Further reading[edit]