ATP5G2

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ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
Identifiers
Symbols ATP5G2 ; ATP5A
External IDs OMIM603193 MGI1915192 HomoloGene57052 GeneCards: ATP5G2 Gene
RNA expression pattern
PBB GE ATP5G2 208764 s at tn.png
PBB GE ATP5G2 207552 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 517 67942
Ensembl ENSG00000135390 ENSMUSG00000062683
UniProt Q06055 P56383
RefSeq (mRNA) NM_001002031 NM_026468
RefSeq (protein) NP_001002031 NP_080744
Location (UCSC) Chr 12:
54.03 – 54.07 Mb
Chr 15:
102.66 – 102.67 Mb
PubMed search [1] [2]

ATP synthase lipid-binding protein, mitochondrial is an enzyme that in humans is encoded by the ATP5G2 gene.[1][2]

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. The protein encoded by this gene is one of three precursors of subunit c. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene has multiple pseudogenes.[2]

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