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ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
Symbols ATP5J2 ; ATP5JL
External IDs MGI1927558 HomoloGene3594 IUPHAR: 806 GeneCards: ATP5J2 Gene
EC number
RNA expression pattern
PBB GE ATP5J2 202961 s at tn.png
More reference expression data
Species Human Mouse
Entrez 9551 57423
Ensembl ENSG00000241468 ENSMUSG00000038690
UniProt P56134 P56135
RefSeq (mRNA) NM_001003713 NM_020582
RefSeq (protein) NP_001003713 NP_065607
Location (UCSC) Chr 7:
99.05 – 99.06 Mb
Chr 5:
145.18 – 145.19 Mb
PubMed search [1] [2]

The ATP5J2 gene [1][2] encodes the ATP synthase subunit f, mitochondrial enzyme in humans.


Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the f subunit of the F0 complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[2]


Further reading[edit]