An abdominoperineal resection, formally known as abdominoperineal resection of the rectum and abdominoperineal excision of the rectum or simply abdominoperineal excision,or the Miles operation is a surgery for rectal cancer or anal cancer. It is frequently abbreviated as AP resection and APR.
Indication and description
The principal indication for AP resection is a rectal carcinoma situated in the distal (lower) one-third of the rectum. Other indications include recurrent or residual anal carcinoma (squamous cell carcinoma) following initial, usually definitive combination chemoradiotherapy.
APRs involves removal of the anus, the rectum and part of the sigmoid colon along with the associated (regional) lymph nodes, through incisions made in the abdomen and perineum. The end of the remaining sigmoid colon is brought out permanently as an opening, called a colostomy, on the surface of the abdomen.
Centralisation of rectal surgery
This operation is one of the less commonly performed by general surgeons, although they are specifically trained to perform this operation. As low case volumes in rectal surgery have been found to be associated with higher complication rates, it is often centralised in larger centres, where case volumes are higher.
There are several advantages in terms of outcomes if the surgery can be performed laparoscopically
Relation to low anterior resection (LAR)
An APR, generally, results in a worse quality of life than the less invasive lower anterior resection (LAR). Thus, LARs are generally the preferred treatment for rectal cancer insofar as this is surgically feasible.
It is named for William Ernest Miles (1869–1947), an English surgeon who devised it in 1923.
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