Acanthocyte
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For the stellate cells found on the hyphae of fungi of the genus Stropharia, see Acanthocyte (mycology).
Acanthocyte, in human biology and medicine, refers to a form of red blood cell that are spiked, or possess various abnormal thorny projections. [1] Acanthocytosis is the condition with acanthocyte-like red blood cells.[2]
These cells are coarse and irregularly crenellated resembling many-pointed stars. They are seen on blood films in, among others, abetalipoproteinemia[3] , liver disease, chorea acanthocytosis, McLeod syndrome and several inherited neurological disorders, such as neuroacanthocytosis.[4]
The term "echinocyte" (or "burr cell") is similar in meaning to "acanthocyte", but implies more moderate spiculation.[5] Burr cells usually imply uremia.
[edit] See also
[edit] References
- ^ "acanthocyte" at Dorland's Medical Dictionary
- ^ Wrongdiagnosis --> Acanthocytosis Retrieved on October 12, 2009
- ^ Cooper RA, Durocher JR, Leslie MH (July 1977). "Decreased fluidity of red cell membrane lipids in abetalipoproteinemia". J. Clin. Invest. 60 (1): 115–21. doi:10.1172/JCI108747. PMC 372349. PMID 874076. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=372349.
- ^ Rampoldi L, Danek A, Monaco AP (2002). "Clinical features and molecular bases of neuroacanthocytosis". J Mol Med 80 (8): 475–91. doi:10.1007/s00109-002-0349-z. PMID 12185448.
- ^ "Spiculated cells (echinocytes and acanthocytes) and target cells". http://www.uptodate.com/patients/content/topic.do?topicKey=~fOTUYEkkyXsiy6M. Retrieved 2009-06-16.
[edit] External links
- Acanthocyte: Presented by the University of Virginia
- MeSH Acanthocytes
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