Acanthocyte
From Wikipedia, the free encyclopedia
Acanthocyte, In human biology and medicine, refers to a form of red blood cells with spikes on it.[1] Acanthocytosis is the condition with acanthocyte-like red blood cells.[2]
These cells are coarse and irregularly crenellated resembling many-pointed stars. They are seen on blood films in, among others, abetalipoproteinemia[3] , liver disease, chorea acanthocytosis, McLeod syndrome and several inherited neurological disorders, such as neuroacanthocytosis.[citation needed]
The term "Echinocyte" (or "burr cell") is similar in meaning to "Acanthocyte", but implies more moderate spiculation.[4]
[edit] References
- ^ acanthocyte at Dorland's Medical Dictionary
- ^ Wrongdiagnosis --> Acanthocytosis Retrieved on October 12, 2009
- ^ Cooper RA, Durocher JR, Leslie MH (July 1977). "Decreased fluidity of red cell membrane lipids in abetalipoproteinemia". J. Clin. Invest. 60 (1): 115–21. doi:. PMID 874076. PMC 372349. http://dx.doi.org/10.1172/JCI108747.
- ^ "Spiculated cells (echinocytes and acanthocytes) and target cells". http://www.uptodate.com/patients/content/topic.do?topicKey=~fOTUYEkkyXsiy6M. Retrieved 2009-06-16.
[edit] External links
- Acanthocyte: Presented by the University of Virginia
- MeSH Acanthocytes
- Slide at marist.edu
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