Aceclofenac

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Aceclofenac
Aceclofenac.png
Systematic (IUPAC) name
2-[2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetyl]oxyacetic acid
Clinical data
Trade names Hifenac, Cincofen, Nacsiv, Acenac
AHFS/Drugs.com International Drug Names
oral, topical
Identifiers
89796-99-6 N
M01AB16 M02AA25
PubChem CID 71771
ChemSpider 64809 YesY
UNII RPK779R03H YesY
KEGG D01545 YesY
ChEBI CHEBI:31159 N
ChEMBL CHEMBL93645 YesY
Chemical data
Formula C16H13Cl2NO4
354.18472 g/mol
 N (what is this?)  (verify)

Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. The dose is 100 mg twice daily.

It should not be given to people with porphyria or breast-feeding mothers, and is not recommended for children.

Aceclofenac has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Aceclofenac is the glycolic acid ester of diclofenac.

Synthesis[edit]

Aceclofenac synthesis.[1]

References[edit]

References[edit]

I am writing this as a patient,I was feeling gastric issue today which was unbearable and was admitted to casualty.I was treated with 3 injections(vaccines:Dikloflame,Buscogast and Esozole 40 mg) which gave me instant relief.Physician gave me 2 tablets one is for gastric and other as pain killer.The pain killer salt includes Aceclofenac 100 mg, Peracetamol 325 mg and Serratiopeptidase 15 mg which I was asked to consume when feel pain. What I found that when I feel same kind of pain the pain killer did the same thing that the vaccines did and I got relief in just 20 minutes.