Aceclofenac

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Aceclofenac
Systematic (IUPAC) name
2-[2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetyl]oxyacetic acid
Identifiers
CAS number 89796-99-6
ATC code M01AB16 M02AA25
PubChem 71771
Chemical data
Formula C16H13Cl2NO4 
Mol. mass 354.18472 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

POM(UK)

Routes oral, topical


Aceclofenac is a non-steroidal anti-inflammatory drug. It is manufactured by Intas Biopharmaceuticals, under the tradename Hifenac in various forms (tablets, gel, injection etc.). Another trade name is Acetal.

It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. The dose is 100mg twice daily. It should not be given to people with porphyria or breast-feeding mothers, and is not recommended for children.

[edit] References

it have higher antiinflammatory action more than the conventional NSAIDS

cytokine inhibitor Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation