Aceglatone

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Aceglatone
Aceglatone.svg
Systematic (IUPAC) name
(3R,3aR,6S,6aR)-2,5-Dioxohexahydrofuro[3,2-b]furan-3,6-diyl diacetate
Clinical data
Trade names Glucaron
AHFS/Drugs.com International Drug Names
Legal status ?
Identifiers
CAS number 642-83-1 N
ATC code None
PubChem CID 636372
ChemSpider 599998 YesY
UNII 347Q3OOJ13 YesY
ChEMBL CHEMBL2103781 N
Synonyms D-Glucaric acid di-γ-lactone 2,5-diacetate
2,5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone
2,5-Di-O-acetyl-D-glucosaccharo-1,4:6,3-dilactone
Chemical data
Formula C10H10O8 
Mol. mass 258.18 g/mol
Physical data
Melt. point 185–186 °C (365–367 °F) [1]
 N (what is this?)  (verify)

Aceglatone (Glucaron) is an antineoplastic drug available in Japan.[2]

It is an inhibitor of the enzyme β-glucuronidase.[3]

References[edit]

  1. ^ Merck Index, 11th Edition, 20
  2. ^ Glucaron, drugs.com
  3. ^ Iida, Ryohei; Nagata, Sachiko; Kakimoto, Morio; Akaike, Hiroaki; Watanabe, Hiroko; Shioya, Akitoshi (1965). "2,5-Di-O-acetyl-D-glucosaccharo-(1→4)(6→3)-dilactone, a new potent β-glucuronidase inhibitor". Japanese Journal of Pharmacology 15 (1): 88–90. doi:10.1254/jjp.15.88.