Acemetacin is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. It is manufactured by Merck under the tradename Emflex, and is available in the UK as a prescription-only drug. Other brand names for acemetacin include Rheutrop (Austria), Acemetadoc, Acephlogont, Azeat, Rantudil (Germany, Mexico), Gamespir (Greece), Oldan, Reudol (Spain), Tilur (Switzerland) ost-map (Egypt).
Acemetacin, a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of acemetacin is that it reduces gastric damage when compared to indometacin.
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Opioids
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Opium & alkaloids thereof
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Semi-synthetic opium
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Synthetic opioids
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Non-steroidal
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Propionic acid class
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Oxicam class
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Acetic acid class
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Anthranilic acid
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Atypical, adjuvant and potentiators,
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