Acetohexamide

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Not to be confused with acetazolamide.
Acetohexamide
Acetohexamide.svg
Acetohexamide ball-and-stick.png
Systematic (IUPAC) name
1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide
Clinical data
Trade names Dymelor
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a602021
Pharmacokinetic data
Protein binding 90%
Identifiers
968-81-0 YesY
A10BB31
PubChem CID 1989
DrugBank DB00414 YesY
ChemSpider 1912 YesY
UNII QGC8W08I6I YesY
KEGG D00219 YesY
ChEBI CHEBI:28052 YesY
ChEMBL CHEMBL1589 YesY
Chemical data
Formula C15H20N2O4S
324.395 g/mol
 YesY (what is this?)  (verify)

Acetohexamide (trade name Dymelor) is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone.

Mechanism of action[edit]

Acetohexamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently.[1] The pancreas must produce insulin for this medication to work. For this reason, acetohexamide is not used to treat diabetes mellitus type 1.

Risks[edit]

Oral hypoglycemic drugs, including acetohexamide, have been associated with increased cardiovascular mortality. Talk to your doctor about the possible risks, benefits, and alternatives of using this drug for your condition.[2]

References[edit]

  1. ^ [1] - Metformin Side Effects
  2. ^ Medline Plus - Acetohexamide