Acetohydroxamic acid

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Acetohydroxamic acid
Systematic (IUPAC) name
ethanehydroxamic acid
Clinical data
AHFS/Drugs.com Consumer Drug Information
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 546-88-3 YesY
ATC code G04BX03
PubChem CID 1990
DrugBank APRD00774
ChemSpider 1913 YesY
UNII 4RZ82L2GY5 YesY
KEGG D00220 YesY
ChEBI CHEBI:49029 YesY
ChEMBL CHEMBL734 YesY
Chemical data
Formula C2H5NO2 
Mol. mass 75.0666 g/mol
SMILES eMolecules & PubChem
 N (what is this?)  (verify)

Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme (Fishbein and Carbone, 1965).

[edit] References

  • W. Fishbein and P. Carbone J Biol Chem. 1965 Jun;240:2407-14

[edit] See also

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