From Wikipedia, the free encyclopedia
Jump to: navigation, search
Skeletal formula
Ball-and-stick model
Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
Legal status
Routes Oral
CAS number 51037-30-0 YesY
ATC code C10AD06
PubChem CID 5310993
ChemSpider 4470534 YesY
KEGG D07190 YesY
Chemical data
Formula C6H6N2O3 
Mol. mass 154.124 g/mol
 YesY (what is this?)  (verify)

Acipimox is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL. Long-term administration is associated with reduced mortality, but unwanted effects limit its clinical use. Adverse effects include flushing (associated with Prostaglandin D2), palpitations, and GI disturbances. Flushing can be reduced by taking aspirin 20-30 min before taking Acipimox. High doses can cause disorders of liver function, impair glucose tolerance and precipitate gout.

Brands available : Acipicap from Zydus Cadila