From Wikipedia, the free encyclopedia
Acronine
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Names
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Preferred IUPAC name
6-Methoxy-3,3,12-trimethyl-3,12-dihydro-7H-pyrano[2,3-c]acridin-7-one
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Other names
Acromycine; Acronycine
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Identifiers
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ChEBI
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ChEMBL
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ChemSpider
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KEGG
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MeSH
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D000175
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UNII
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InChI=1S/C20H19NO3/c1-20(2)10-9-13-15(24-20)11-16(23-4)17-18(13)21(3)14-8-6-5-7-12(14)19(17)22/h5-11H,1-4H3 Key: SMPZPKRDRQOOHT-UHFFFAOYSA-N InChI=1/C20H19NO3/c1-20(2)10-9-13-15(24-20)11-16(23-4)17-18(13)21(3)14-8-6-5-7-12(14)19(17)22/h5-11H,1-4H3 Key: SMPZPKRDRQOOHT-UHFFFAOYAD
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CC1(C=CC2=C3C(=C(C=C2O1)OC)C(=O)C4=CC=CC=C4N3C)C
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Properties
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C20H19NO3
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Molar mass
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321.376 g·mol−1
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Acronine is an anti-tumor chemical that has yielded synthetic anti-tumor derivatives.[1]
References[edit]
- ^ Neto, Miguel; Dacosta, João; Sant'Anna, Carlos; Carneiro, José (2005). "Structure-activity relationship studies of new acronine analogues as suggested by molecular descriptors". Arzneimittelforschung. 55 (5): 282–8. doi:10.1055/s-0031-1296858. PMID 15960428. S2CID 22306664.