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- OAA Old Age Assistance
- OASDHI Old Age Survivors, Disability, and Health Insurance Program
- OBRA Omnibus Budget Reconciliation Act
- OD Overdose or the right eye (from the Latin)
- ODS Organized Delivery System
- OMB Office of Management and Budget
- OPD Outpatient Department
- OPHP Office of Public Health Preparedness
- OS The left eye (from the Latin)
- OSHA Occupational Health and Safety Administration
- QALY Quality-Adjusted Life Year
- QAPI Quality Assessment and Performance Improvement Program
- QARI Quality Assurance Reform Initiative
- QD Each day, usually in prescriptions.
- QIO Quality Improvement Organization
- QISMC Quality Improvement System for Managed Care
- QuICQuality Interagency Coordination Task Force
- VIRHN Vertically Integrated Rural Health Network
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