Acute chest syndrome
Classification and external resources
acute chest syndrome is a vaso-occlusive crisis of the pulmonary vasculature commonly seen in patients with sickle cell anemia. This condition commonly manifests with pulmonary infiltrate on a chest x-ray. [1 ]
Acute chest syndrome is often precipitated by a lung infection, and the resulting
inflammation and loss of oxygen saturation leads to further sickling of red cells, thus exacerbating pulmonary and systemic hypoxemia, sickeling, and vaso-occlusion.
Symptoms [ edit ]
The crisis is a common complication in sickle-cell patients and can be associated with one or more symptoms including fever, cough,excruciating pain,
sputum production, dyspnea, or hypoxia. [2 ]
Treatment [ edit ]
Broad spectrum antibiotics to cover common infections like strep pneumoniae and mycoplasma, pain control, and blood transfusion. Acute chest syndrome is an indication for exchange transfusion.
Prognosis [ edit ]
It may result in death,
and it is one of the most common causes of death for sickle cell patients. [3 ] [4 ]
See also [ edit ]
References [ edit ]