Acute chest syndrome
| Acute chest syndrome | |
|---|---|
| Classification and external resources | |
| ICD-9 | 517.3 |
The acute chest syndrome is a noninfectious[1] vaso-occlusive crisis of the pulmonary vasculature commonly seen in patients with sickle cell anemia.
It is characterized by a new infiltrate on a chest x-ray.[2]
Contents |
[edit] Cause
The crisis is often initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion.
[edit] Symptoms
The crisis is a common complication in sickle-cell patients and can be associated with one or more symptoms including fever, cough, sputum production, dyspnea, or hypoxia. [3]
[edit] Treatment
Broad spectrum antibiotics to cover common infections like strep pneumoniae and mycoplasma, Pain control, and Blood transfusion.
[edit] Prognosis
It may result in death,[4] and it is one of the most common causes of death for sickle cell patients.[5]
[edit] See also
[edit] References
- ^ Mary Lieh-Lai; Katherine A Ling-McGeorge; Maria C Asi-Bautista (1 July 2001). Pediatric acute care. Lippincott Williams & Wilkins. pp. 88–. ISBN 978-0-7817-2852-2. http://books.google.com/books?id=tXhvOAgT7wgC&pg=PA88. Retrieved 15 June 2010.
- ^ Betty Pace (2007). Renaissance of Sickle Cell Disease Research in the Genome Era. Imperial College Press. pp. 81–. ISBN 978-1-86094-645-5. http://books.google.com/books?id=mhqswaCtcLQC&pg=PA81. Retrieved 15 June 2010.
- ^ Johnson, CS (1995). "Sickle-Cell Disease: The Acute Chest Syndrome". http://sickle.bwh.harvard.edu/acutechest.html.
- ^ "acute chest syndrome" at Dorland's Medical Dictionary
- ^ Kumar, Abbas, Fausto. Robbins and Cotran: The Pathologic Basis of Disease, Page 631
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