|Pregnancy cat.||C (US)|
|Legal status||℞ Prescription only|
|ATC code||D10, D10|
|(what is this?)|
Adapalene/benzoyl peroxide is a prescription drug combination for the treatment of acne, marketed by Galderma under the trade name Epiduo. (Its trade name is Tactuo in Canada.) It consists of a combination of adapalene (0.1%) and benzoyl peroxide (2.5%) in a topical ointment. This preparation does not create any bacterial resistance during long term application.
Patients are advised to exercise caution in using Epiduo together with other skin products containing sulfur, resorcinol, or salicylic acid, or with medicated or abrasive dirts and cleansers. Skin products with high levels of alcohol or astringents should also be avoided. Using topical products with a strong drying effect in combination with Epiduo can increase irritation.
Commonly reported side effects include:
Apply topically after gently washing the areas the product will be applied with a non-medicated soap. Apply a thin layer to the affected area. Avoid contact of the product with the eyes, lips, and mucous membranes. 
- "FDA OKs New Acne Gel Epiduo". Webmd.com. Retrieved 2012-01-25.
- "Full prescribing information" (PDF). Retrieved 2012-01-25.
- >PharmacisAnswers Acne Products Webpage Retrieved Feb 13, 2014
- Epiduo (adapalene and benzoyl peroxide) gel package insert. Fort Worth, TX: Galderma Laboratories, L.P.; 2011 June
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