Adenosine-tetraphosphatase

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adenosine-tetraphosphatase
Identifiers
EC number 3.6.1.14
CAS number 37289-26-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an adenosine-tetraphosphatase (EC 3.6.1.14) is an enzyme that catalyzes the chemical reaction

adenosine 5'-tetraphosphate + H2O \rightleftharpoons ATP + phosphate

Thus, the two substrates of this enzyme are adenosine 5'-tetraphosphate and H2O, whereas its two products are ATP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is adenosine-tetraphosphate phosphohydrolase. This enzyme participates in purine metabolism.

Structural studies[edit]

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2V7Q.

References[edit]

  • Small GD, Cooper C (1966). "Purification and properties of nucleoside tetraphosphate hydrolase from rabbit muscle". Biochemistry. 5 (1): 14–26. doi:10.1021/bi00865a003. PMID 4287215.