She was married to the wealthy merchant Gerrit Listincx. She was in 1525, 1527, 1530 and 1533 put on trial for violating the religious laws. In 1535, banned books were found in her possecion and her son stated, during an interrogation for heresy, that his mother was in the Anabaptist ruled Münster. In Münster, Aefgen Listincx was active as a prophet. She was captured after the fall of Münster but released because of her wealth. In 1538, she was put on trial for heresy and executed by burning.
She was likely the sister of Alejid Leystingh.