Aglepristone

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Aglepristone
Aglepristone.png
Systematic (IUPAC) name
(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-[(1Z)-1-propen-1-yl]estra-4,9-dien-3-one
Clinical data
Identifiers
124478-60-0
G03XB90
PubChem CID 14153279
ChemSpider 16736563
Chemical data
Formula C29H37NO2
431.610 g/mol

Aglepristone (INN) (brand name Alizine; former code names RU-46534, RU-534) is a steroidal antiprogestin (progesterone receptor full antagonist) related to mifepristone which is marketed by Virbac in several European countries for use in veterinary medicine.[1][2][3] It is specifically used as an abortifacient in pregnant.[1][3][4] Aglepristone, similarly to mifepristone, also possesses some antiglucocorticoid activity.[citation needed]

References[edit]

  1. ^ a b John D. Bonagura; David C. Twedt (1 December 2013). Kirk's Current Veterinary Therapy XV. Elsevier Health Sciences. pp. 3009–. ISBN 978-0-323-22762-9. 
  2. ^ E. James Squires (2010). Applied Animal Endocrinology. CABI. pp. 207–. ISBN 978-1-84593-755-3. 
  3. ^ a b Mark G. Papich (3 November 2010). Saunders Handbook of Veterinary Drugs: Small and Large Animal. Elsevier Health Sciences. pp. 120–. ISBN 1-4377-0192-2. 
  4. ^ Patrick W. Concannon (2001). Advances in reproduction in dogs, cats and exotic carnivores: proceedings of the fourth International Symposium on Canine and Feline Reproduction, Oslo, Norway, 29 June-1 July 2000. Journal of Reproduction and Fertility. ISBN 978-0-906545-37-9.